2022-07-01: more ...
This article explores the correlation between subsets of cancer entities, grouped by their somatic CNV patterns, and levels of diagnostic classification systems.
2021-03-01: more ...
qingyao 2018-09-20: more ...
@mbaudis 2019-07-31: more ...
mbaudis 2019-01-14: more ...
Copy number aberrations (CNA) are one of the most important classes of genomic mutations relatedto oncogenetic effects. In the past three decades, a vast amount of CNA data has been generated bymolecular-cytogenetic and genome sequencing based methods. While this data has been instrumentalin the identification of cancer-related genes and promoted research into the relation between CNA andhisto-pathologically defined cancer types, the heterogeneity of source data and derived CNV profilespose great challenges for data integration and comparative analysis. Furthermore, a majority of exist-ing studies have been focused on the association of CNA to pre-selected ”driver” genes with limitedapplication to rare drivers and other genomic elements.
2021-05-13: more ...
2021-11-30: more ...
This article was published as part of a special GA4GH edition of Cell Genomics.
2021-11-10: more ...
This article provides an overview of recent changes and additions to the Progenetix database and the services provided through the resource.
2021-06-30: more ...